In-Vivo Pharmacokinetics Study
Pharmacokinetic response profiling
The aim of this study is to determine the impact of various animal and dosing characteristics on the absorption of a therapeutic compound into the bloodstream. Analytical data on blood concentration is collected into Riffyn alongside study data characterizing the animal physiology and dosing parameters. Riffyn is used to automatically integrate the data into a statistical data frame and then feed the data frame to JMP for multivariate analysis. Two factors are determined to have a statistically significant impact on adsorption, one is shown to be irrelevant.
Process and experiment design were created, and data were captured and prepared with Riffyn. Plots were created with JMP® Software. Copyright 2018, SAS Institute Inc., Cary, NC, USA. All Rights Reserved. Reproduced with permission of SAS Institute Inc., Cary, NC.
"This type of statistical analysis is very easy with Riffyn because all of the underlying data across the entire experiment is prepared and exported in a statistical data table that can be opened inside your preferred analysis program."
Highlighted in the Video
Data collection & joining
Statistical analysis with JMP