Riffyn Nexus (Riffyn SDE) Published in a Ground-breaking Study in the Journal Scientific Data
Evaluation of a novel cloud-based software platform for structured experiment design and linked data analytics
Hannes Juergens, Matthijs Niemeijer, Laura D. Jennings-Antipov, Robert Mans, Jack Morel, Antonius J. A. van Maris, Jack T. Pronk & Timothy S. Gardner
Riffyn SDE was created to address the crisis in scientific reproducibility and demands for more cost-efficient drug development. Its potential to transform the quality and reusability of scientific work was recently demonstrated in a ground-breaking study published in Scientific Data by Delft University of Technology and Riffyn. The study harnessed Riffyn SDE to execute a complex set of microbial fermentation experiments.
“Riffyn SDE’s systematic description of experimental methods eliminates many limitations that are inherent to traditional lab protocols and methods sections in journals,” explained Dr. Jack Pronk, Professor of Industrial Microbiology at Delft University of Technology and co-author of the study. “I expect this type of detailed, web-based description of experimental procedures to become the new standard in scientific publications, thereby increasing the repeatability of scientific research and facilitating meaningful reuse of published data.”
The Delft study utilized Riffyn SDE to fully define, capture, analyze, and publish a set of scientific experiments in much the same way that CAD software is used to design, test and improve discrete products. Notably, the Scientific Data article replaced the standard materials and methods section in the body of the publication with a link to the comprehensive experiment designs and data in Riffyn SDE itself. Riffyn SDE delivers all experimental methods, their associated data, and their analysis scripts in a modular, reusable, and instantly computable digital medium.
Tim Gardner is the Founder and the CEO of Riffyn. He was previously Vice President of Research & Development at Amyris, where he led the engineering of yeast strain and processes technology for large-scale bio-manufacturing of renewable chemicals. Tim has been recognized for his pioneering work in Synthetic Biology by Scientific American, the New Scientist, Nature, Technology Review, and the New York Times. He also served as an advisor to the European Union Scientific Committees and the Boston University Engineering Alumni Advisory Board. Tim enjoys hockey, running, mountain biking, and being beaten by his sons in almost everything.